Results: 1188

For: Populations and settings

Community-based oral health promotion interventions

The review found that adding family-based interventions to school-based interventions may reduce the onset of smoking by 4-25%.

This Cochrane review of community-based oral health promotion interventions included 38 studies and suggests that interventions combining oral health education with supervised toothbrushing or professional preventive oral care can reduce dental caries in children.

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Depression and coronary heart disease: reasons to remain UPBEAT-UK

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Kirsten Lawson summarises the UPBEAT-UK programme of research into the relationship between coronary heart disease and depression and anxiety in primary care patients.

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Fitness to practice: exercise for depression in adolescents

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Dave Steele warms up for the winter triathlon season by reading a new systematic review on the effect of exercise on depressive symptoms in adolescents.

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Dementia in Down syndrome: Are we ready for a clinical trial?

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Leen Vereenooghe summarises the TOP-COG study (Towards Onset Prevention of COGnitive decline in adults with Down syndrome). This pilot RCT highlights the need to educate people with learning disabilities and their carers about the importance of research participation.

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The case for investing in anxiety and depression treatment on a global scale

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Chris Sampson looks at a major new economic study into the return on investment of increased coverage for anxiety and depression treatment.

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What does patient and public involvement feel like?

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Alison Turner explores a recent study of patient and public involvement in clinical commissioning, which found that PPI representatives are often uncertain about their role and how their contribution is used.

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Third molars: insufficient evidence for removal of impacted asymptomatic disease-free teeth

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This update of an earlier Cochrane review comparing retention or extraction of of asymptomatic disease-free impacted third molars only identified 2 studies of low to very low quality evidence providing insufficient evidence to inform practice.

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Early menarche associated with depressive symptoms in early adolescence

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Emily Stapley summarises a Mendelian randomisation study that investigates associations between the timing of menarche with depressive symptoms and depression in adolescence.

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Behavioural activation not inferior to CBT for depression: the COBRA RCT

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Ioana Cristea appraises the recently published COBRA randomised controlled trial, which concludes that behavioural activation is non-inferior to cognitive behavioural therapy for depression, and may offer significant cost savings.

This blog also features a podcast interview with the lead author: Professor David Richards from Exeter University.

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What is the evidence for evidence-based guidelines?

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Andrew Shepherd returns to the woodland with a blog about the evidence-practice gap in specialist mental healthcare; highlighting a recent systematic review and meta-analysis of guideline implementation studies.

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